P-078 Neoadjuvant epirubicin, oxaliplatin and capecitabine (EOX) in locally advanced resectable gastroesophageal junction and gastric adenocarcinoma: the experience in our institution
نویسندگان
چکیده
منابع مشابه
شیمی‌درمانی نئواجوانت با رژیم اپی‌روبیسین، اگزالی‌پلاتین و کپیستابین در سرطان موضعی پیشرفته‌ی معده: مطالعه دو ساله
Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is the standard treatment for locally advanced gastroesophageal junction (EGJ) cancers. The purpose of this study was to evaluate response and tolerability to neoadjuvant regimen combining epirobicin, oxaliplatin and capecitabin (EOX) in locoregionally advanced gastric ca...
متن کاملResponse to neoadjuvant chemotherapy in locally advanced gastric and gastroesophageal cancer: Phase II clinical trial
Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. The purpose of this investigation was evaluation of response and tolerability to neoadjuvant EOX regimen in locoregionally advanced gastric cancer. Materials and Methods: patients with locoregionally adv...
متن کاملEfficacy of preoperative chemotherapy regimens in patients with initially unresectable locally advanced gastric adenocarcinoma: capecitabine and oxaliplatin (XELOX) or with epirubicin (EOX)
Purpose We assessed the effectiveness of EOX (capecitabine, oxaliplatin and epirubicin) compared with XELOX (capecitabine and oxaliplatin) as preoperative chemotherapy for initially unresectable locally advanced gastric cancer.Methods This is a prospective observational study. Patients with unresectable locally advanced gastric cancer were performed EOX regimen or XELOX regimen at the discretio...
متن کاملPhase II study of epirubicin, oxaliplatin and docetaxel combination in metastatic gastric or gastroesophageal junction adenocarcinoma
BACKGROUND This phase II study was designed to evaluate the activity and safety of a combination of epirubicin, oxaliplatin and docetaxel in metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma. METHODS Forty patients with measurable distant metastases received epirubicin 50 mg/m2, docetaxel 60 mg/m2 followed by oxaliplatin 100 mg/m2 on day 1 of each 21-day cycle. Primary end ...
متن کاملNeoadjuvant chemotherapy in locally advanced gastric adenocarcinoma: our experience in the elderly
Background Gastric cancer is a neoplasm with a poor prognosis, often diagnosed in advanced stage of disease, specially in elderly patients. Neo-adjuvant chemotherapy may increase the possibility of complete surgical resection, improving progression-free and overall survival (five-years survival of 36% compared with 23% of patients treated by surgery alone) as shown in the MAGIC Trial by Cunning...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1093/annonc/mdw199.76